Mewgenics Guide: How to Unlock Every Grueling Achievement

You are going to harvest a mountain of feline organs to finish this game, so you might as well track your milestones efficiently.

Mewgenics gameplay shows mutated cat characters battling a grotesque, multi-eyed Coven boss in a dark, bone-filled dungeon arena.

Getting every single achievement in Mewgenics is going to cost you a terrifying amount of dead cats and whatever remains of your real world social life. When I first looked at the global completion stats for this roguelike, I actually laughed out loud. Barely anyone has cracked the endgame trophies. Edmund McMillen designed this nightmare to be a grueling generational grind. You are not meant to beat everything in a weekend. You are meant to breed an army of freaks, watch them die horribly, scrape up their remains, and try again.

The achievement list reflects that exact gameplay loop. There are 281 milestones and quite a few of them are completely hidden from the player. You just stumble into them by repeatedly throwing your beloved pets into the Boneyard. If you are barely surviving the Sewers right now, do yourself a massive favor and study my Beginner's Guide before reading further. You need foundational knowledge before you worry about full completion.

For those of you ready to suffer, I stretched out the massive achievement list into logical, readable categories. No more squinting at a wall of text. You can actually plan your runs instead of relying on blind luck.

The Hoarder's Tax

The easiest achievements involve the economic metagame happening inside your house. The weirdos living around your property demand constant tribute. Supplying them with living kittens, adult cats, or fresh corpses is how you upgrade your base. Tink wants kittens to unlock breeding modifiers. Frank needs adults to expand your house. The Mystery Man is running an organ trafficking ring and demands massive piles of dead cats.

If you want to optimize your living space to keep your cats happy before shipping them off to die, check out my House Design Guide.

NPC Tribute Achievements

Hoarding felines is a legitimate survival strategy.

Achievement Group The Unlock Requirement
Frank's House Upgrades Send Frank increasing amounts of adult cats. This unlocks four separate achievements from the Attic up to the 4th room expansion.
Butch's Storage Send Butch batches of cats to slowly unlock Storage upgrade 1 through Storage upgrade 7.
Tracy's Hoard Send Tracy a ridiculous amount of cats. This massive grind unlocks ten Food Storage upgrades, three Blank Collar slots, and seven Mysterious Idols.
Tink's Breeding Tags Send Tink live kittens. This grants seven distinct rewards including vital breeding modifiers like Inbreeding, Aggression, and Base Stats.
Jack's Shack Upgrades Send Jack cats to expand his shop inventory. This pops four separate shack upgrade achievements.
Mystery Man's Organ Ring Send strictly dead cats to the creepy guy in the yard. This unlocks seven grim organ harvesting upgrades.

Map Unlocks and Narrative Encounters

Progression in Mewgenics is mostly linear, but there are a few hidden zones and bizarre narrative sidequests to track down.

Exploration and Quests

Survive long enough and you might actually see the end of time.

Map or Quest Category The Trophies Unlocked
Standard Map Progression Complete the previous zone to unlock The Sewers, The Caves, The Boneyard, The Desert, The Bunker, The Crater, The Moon, and The Core.
Alternate Map Paths Unlock The Junkyard by taking the hard path in the Alley. Fix the time machine for The Iceage. Pushing further unlocks The Jurassic, The Future, and The End.
Secret Quest Domains Collect specific quest items to unlock access to The Throbbing Domain, The Rift, and The Infinite.
Beanie's Science Quests Find Beanie to unlock weird item quests like Nuclear Knife, Spider Injector, Glass Cannon, Magic Mirror, Stopwatch, and Unidentified Pills.
Beanie's Social Encounters Trigger random events to unlock narrative trophies like Fart Face, The Loner, Angry Face, Bubble Boy, Redacted, Party Detonator, and Princess Hat.
Boss Collars Help Zaratana or Pyrophina win their specific fight event to unlock Zaratanas Collar or Pyrophinas Collar.

Class Mastery and The Meat Grinder

Mewgenics forces you to run a gauntlet with every single class. You have the Fighter, Mage, Thief, Druid, Butcher, Psychic, Monk, Jester, Tinkerer, Necromancer, Cleric, Tank, Hunter, and the basic Collarless cats.

You need pristine genetics to survive the later maps with the weaker classes. Read up on my Breeding & Genetics Guide so you know exactly which shapes and stats to isolate. When a good cat inevitably ages out of combat viability, do not toss them away. My Retired Veterans Guide shows you how to extract value from elderly soldiers.

Early Class Run (Abilities & Passives)

The first half of your class mastery checklist.

The Class Pairings The Base Unlocks
Cleric & Tank Completing the Caves unlocks Ethereal and Suplex. Beating the Boneyard unlocks Evil Patron and Bouncer.
Hunter & Fighter Completing the Caves unlocks Ball of Spiders and Paw Breaker. Beating the Boneyard unlocks Thrill Of The Hunt and Dual Wield.
Mage & Thief Completing the Caves unlocks Hyper Beam and Nail Flurry. Beating the Boneyard unlocks Three and First Strike.
Necromancer & Druid Completing the Caves unlocks Summon Shade and Summon Bear. Beating the Boneyard unlocks Servus Mortem and Suicide Squad.
Tinkerer & Butcher Completing the Caves unlocks Mech Suit and Slice And Dice. Beating the Boneyard unlocks Armor Specialist and Indigestion.
Psychic & Monk Completing the Caves unlocks Supernova and Hundred Hand Slap. Beating the Boneyard unlocks Gravity Well and Unstoppable.
Jester & Collarless Completing the Caves unlocks Smart Metronome and Metronome. Beating the Boneyard unlocks Super Luck & Goofball and Skill Share.

Once you have your base skills, the game demands you take those classes into the endgame zones for the final pieces of their kit.

Late Game Class Trophies

Prepare to lose a lot of good cats here.

Completion Action The General Unlocks
Complete The Core Unlocks the specific Colorless Ability for whichever class you are playing (e.g., Path Of The Cleric, Path Of The Tank, Path Of The Void).
Complete The Moon Unlocks the specific Colorless Passive for your active class (e.g., Clerics Soul, Tanks Soul, Void Soul).
Defeat The King Unlocks Class Helmets like the Cleric's Mitre, Tank Helmet, Spider Hat, Scrappers Hat, and Tinfoil Hat.
Defeat Chaos Unlocks Class Face items like Cleric Tears, Tank Tattoo, Death Mask, Scrappers Mask, and Mystic Eye.
Defeat The Creator Unlocks Class Necklaces like the Cleric Relic, Tank Pads, Leech Necklace, Scrappers Backpack, and Diviners Cloth.
Complete The Jurassic Unlocks Class Weapons like the Anointing Oil, Girder, Staff of the Underworld, Ball Peen Hammer, and Bent Spoon.
Complete The End Unlocks primary Class Trinkets like the Prayer Card, Tank Juice, Satanic Bible, Scrap Bag, and Tarot Deck.

The Masochist Tiers: Bosses on Impossible

Everything I mentioned above is just a warm up. The true gatekeepers of the 100 percent completion club are the difficulty modifiers.

The game demands you defeat every major boss on Hard, Crazy, and Impossible difficulties. I strongly recommend keeping my Boss Strategies Guide open on a second monitor while you attempt these fights. The mechanics change drastically on higher difficulties and going in blind guarantees a total wipe. You will also need to abuse every glitch and mechanical quirk available, which I catalog in my Advanced Tips & Secrets breakdown.

The Steven Variants and The Box

Only genuine psychopaths will earn these final trophies.

Achievement Category The Painful Requirement
Hard Mode Boss Trophies Defeat bosses on Hard. Earn specific gross items like Tinas Belly Button, Tinas Larynx, Zaratana Turd, Pyrophinas Toenail, and Crown Of Chaos.
Crazy Mode Boss Trophies Defeat bosses on Crazy. This unlocks the "Stevens" gear collection, including Stevens Gobbler, Stevens Fart Face, Stevens Shotgun, and Stevens Gristle.
Impossible Mode Boss Kills Defeat bosses on Impossible. You earn an identically named "Steven" achievement for every single boss kill on the hardest difficulty.
The Copy Cat Run Defeat the King, Chaos, and the Creator using a team entirely composed of Collarless cats. This unlocks Copy Cat 1, 2, and 3.
The Ultimate Box Challenge Complete all chapters with every class on Normal (The Box), Hard (The bOx), Crazy (The boX), and finally, Impossible (the box).

Achieving 100 percent in Mewgenics proves you have mastered a deliberately unfair system. Keep breeding, keep hoarding organs, and accept that your favorite cats are absolutely going to die for the greater good.

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